Fragile X Syndrome Research Study​

DO YOU CARE FOR A CHILD, ADOLESCENT OR YOUNG ADULT WITH FRAGILE X?

People with Fragile X syndrome (FXS) often experience behavioral symptoms such as:
Anxiety

Anxiety — particularly social anxiety / avoidance

Irritability
Irritability
Tantrums
Tantrums
Social unresponsiveness
Social unresponsiveness

The behavioral symptoms associated with a Fragile X diagnosis can create daily challenges for your child, your family and you. A clinical trial known as RECONNECT is currently enrolling participants to evaluate an investigational, topical treatment that may help improve Fragile X-related behavioral symptoms.

Doctor

WHAT ARE THE RECONNECT STUDY QUALIFICATIONS?

3-22 Years Old

Between the ages of 3 and 22

FragileX

Diagnosed with FXS via genetic testing

Behavioral Symptoms

Experiencing behavioral symptoms of FXS

Healthy

In generally good health

WHAT IS THE STUDY MEDICATION?

The study medication is pharmaceutically produced cannabidiol (not extracted from the cannabis plant). It comes as a clear topical gel that is applied directly to the skin by rubbing into the upper arm and shoulder (like you would rub in sunscreen).

WILL A CANNABIDIOL TREATMENT CAUSE MY CHILD TO GET “HIGH”?

The study medication is pharmaceutically produced cannabidiol that contains no THC, which is the element of cannabis that causes a euphoric or “high” effect. Thus, there is no “high” experienced by children participating in the study.
Study Medication

HOW IS THE MEDICATION ADMINISTERED?

The dose of study medication depends on the weight of the participant:

≤ 66 lbs (30 kg)

2 packets

2 PACKETS OF GEL/DAY

> 66 lbs (30 kg) to ≤ 110 lbs (50 kg)

4 packets

4 PACKETS OF GEL/DAY

> 110 lbs (50 kg)

6 packets

6 PACKETS OF GEL/DAY

Parents or caregivers will be instructed on proper application of the gel to clean, dry, intact skin of the upper arms/shoulders.

RECONNECT IS BEING CONDUCTED AT CENTERS ACROSS THE U.S. OR AT PARTICIPANTS’ HOMES.

In-Clinic Locations on US Map

OPTION 1: IN-CLINIC

in_clinic virtual visits and appointments
At-Home

OPTION 2: AT-HOME

at-home virtual visits and appointments